4-Ethyl-1,3-thiazol-2-amine hydrochloride
4-Ethyl-1,3-thiazol-2-amine hydrochloride
CAS: 34631-53-3
Molecular Formula: C5H8N2S
4-Ethyl-1,3-thiazol-2-amine hydrochloride - Names and Identifiers
4-Ethyl-1,3-thiazol-2-amine hydrochloride - Physico-chemical Properties
| Molecular Formula | C5H8N2S |
| Molar Mass | 128.2 |
| Density | 1.195±0.06 g/cm3(Predicted) |
| Melting Point | 35 °C |
| Boling Point | 118-120 °C |
| pKa | 5.42±0.10(Predicted) |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD17976987 |
4-Ethyl-1,3-thiazol-2-amine hydrochloride - Introduction
4-Ethyl-1,3-thiazol-2-amine hydrochloride, also known as 4-Ethyl-1,3-thiazol-2-amine hydrochloride, its chemical formula is C6H7N3S · HCl. The following is a description of the properties, uses, preparation and safety information of the compound:
1. nature:
-Appearance: This is a white to light yellow solid.
-Melting point: about 165-168°C.
-Solubility: Can be dissolved in water and some organic solvents.
2. use:
- 4-Ethyl-1,3-thiazol-2-amine hydrochloride is an important organic synthesis intermediate, which can be used to synthesize various drugs and bioactive molecules.
-It can also be used as a synthetic intermediate for dyes and photosensitive materials.
3. preparation method:
The preparation of 4-Ethyl-1,3-thiazol-2-amine hydrochloride can be carried out by the following steps:
1) At room temperature, 4-ethyl-2-pyridone is reacted with sulfuric acid, nitric acid and caustic soda to obtain 4-ethylthiazol-2-ol.
2) React 4-ethylthiazol-2-ol with 1,3, 4-trichlorothiobenzoone to generate 4-Ethyl-1,3-thiazol-2-amine hydrochloride.
3) 4-Ethyl-1,3-thiazol-2-amine hydrochloride is reacted with hydrochloric acid to obtain 4-Ethyl-1,3-thiazol-2-amine hydrochloride hydrochloride.
4. Safety Information:
- 4-Ethyl-1,3-thiazol-2-amine hydrochloride may be irritating to the eyes, skin and respiratory system.
-During use and storage, care should be taken to avoid contact with oxidants and strong acids.
-In the operation, should comply with the safe operation procedures, and equipped with a good ventilation system.
1. nature:
-Appearance: This is a white to light yellow solid.
-Melting point: about 165-168°C.
-Solubility: Can be dissolved in water and some organic solvents.
2. use:
- 4-Ethyl-1,3-thiazol-2-amine hydrochloride is an important organic synthesis intermediate, which can be used to synthesize various drugs and bioactive molecules.
-It can also be used as a synthetic intermediate for dyes and photosensitive materials.
3. preparation method:
The preparation of 4-Ethyl-1,3-thiazol-2-amine hydrochloride can be carried out by the following steps:
1) At room temperature, 4-ethyl-2-pyridone is reacted with sulfuric acid, nitric acid and caustic soda to obtain 4-ethylthiazol-2-ol.
2) React 4-ethylthiazol-2-ol with 1,3, 4-trichlorothiobenzoone to generate 4-Ethyl-1,3-thiazol-2-amine hydrochloride.
3) 4-Ethyl-1,3-thiazol-2-amine hydrochloride is reacted with hydrochloric acid to obtain 4-Ethyl-1,3-thiazol-2-amine hydrochloride hydrochloride.
4. Safety Information:
- 4-Ethyl-1,3-thiazol-2-amine hydrochloride may be irritating to the eyes, skin and respiratory system.
-During use and storage, care should be taken to avoid contact with oxidants and strong acids.
-In the operation, should comply with the safe operation procedures, and equipped with a good ventilation system.
Last Update：2024-04-09 02:00:56
